The human pattern of gyrification in the cerebral cortex.

Bibliographic Collection: 
MOCA Reference, APE
Publication Type: Journal Article
Authors: Zilles, K; Armstrong, E; Schleicher, A; Kretschmann, H J
Year of Publication: 1988
Journal: Anat Embryol (Berl)
Volume: 179
Issue: 2
Pagination: 173-9
Date Published: 1988
Publication Language: eng
ISSN: 0340-2061
Keywords: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Body Height, Body Weight, Cerebral Cortex, Female, Humans, Male, Middle Aged, Organ Size, Sex Characteristics

The degree of cortical folding found in adult human brains has been analyzed using a gyrification index (GI). This parameter permits the description of a mean value for the whole brain, but also a local specific analysis of different brain regions. Correlation analyses of the GI with age, body weight, body length, brain weight and volume of the prosencephalon and the cortex show no significant results. GI values do not differ significantly between male and female brains, right and left hemispheres or right and left sides of the superior temporal plane. The GI shows maximal values over the prefrontal and the parieto-temporo-occipital association cortex. A comparison between the rostro-caudal GI patterns of human brains and those of prosimians and Old World monkeys shows the largest difference over the prefrontal cortex. The mean GI increases from prosimians to human brains with the highest values for non-human primates being in the pongid group.

Alternate Journal: Anat. Embryol.