Serum Lp(a) Level

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Serum lipoprotein Lp(a) concentrations vary considerably among humans and are primarily determined by the apo(a) gene locus. Mean plasma Lp(a) levels in the chimpanzee are significantly higher than those observed in humans (Doucet, C., Huby, T., Chapman, J., and Thillet, J. (1994) J. Lipid Res 35, 263-270). This is likely due to high transcriptional activity of the chimpanzee apo(a) gene. (Huby T J Biol Chem. 2001 Jun 22;276(25):22209-14. Epub 2001 Apr 11. PMID: 11301336). 

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